The gut microbiome (i.e: the microorganisms present in our intestine)
plays a major role in maintaining our health. In case of dysfunction, the microbiome
is linked to a large number of inflammatory, metabolic, and neurological diseases.
The study of the microbiome opens many perspectives for tomorrow’s medicine.
For a decade, the intestinal microbiome has generated increasing interest, as
evidenced by the growing number of scientific publications associated with the
intestinal microbiome.
These results pave the way to many perspectives for tomorrow’s medicine in
nutrition, diagnosis, personalized care and explain the growing interest and
investments in the microbiome field by health and nutrition companies as well as
academics.
Unfortunately, current methods of sampling the human intestinal microbiome are limited:
- Animal models are difficult to transpose to humans
- Faecal analysis, most commonly used and simple to implement, does not allow a
representative analysis of the in-situ microbiome
- Endoscopy is expensive, invasive and is complex to carry out on a large scale
APPLICATIONSIt is well established that the intestinal microbiome has an intimate
relationship with the other organs of the body and is linked to several
diseases as diverse as:
- diabetes
- obesity
- inflammatory bowel disease
- cancer
- neurodegenerative diseases
- rheumatoid arthritis
- cardiovascular diseases
- depression
- autism
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